PTM & Glycosylation Profiling
WE CHARACTERIZE POST-TRANSLATIONAL MODIFICATIONS (PTMs) AND GLYCOSYLATION PATTERNS
Which are critical quality attributes for biologics and biosimilars.
Benefit
- Ensures product safety and efficacy
- Supports biosimilar comparability and lifecycle management
- Robust datasets for regulatory submissions
Techniques & Methods
PTM mapping
Oxidation, deamidation, phosphorylation, acetylation, etc.
N- and O-glycan analysis
enzymatic release + HILIC/LC-MS